Cancer is an extremely complex subject, so I’d recommend reading his summary article in which he outlines, in fairly simple language, the foundation of his argument.
Aneuploidy Theory refers to the idea that certain health conditions and disorders can occur when there are abnormalities in the number of chromosomes in our cells.
Chromosomes are like tiny packages inside our cells that contain our genetic material, including our DNA. Normally, humans have 46 chromosomes, which come in 23 pairs. However, sometimes, mistakes can happen during the process of cell division, which can lead to an abnormal number of chromosomes in a cell.
This condition is called aneuploidy.
Aneuploidy means that a cell may have too many or too few chromosomes compared to the usual 46. For example, instead of having two copies of a particular chromosome, there may be three or only one. These abnormalities can occur in any of the chromosomes in our cells.
Moreover, such changes in chromosome numbers can lead to health problems such as Down Syndrome, which is caused by an extra copy of chromosome 21.
In the context of cancer, Aneuploidy Theory suggests that abnormalities in the number of chromosomes can be a cause.
Which is a departure from the established consensus because it challenges the long-standing view that cancer development is primarily driven by specific gene mutations, known as the Somatic Mutation Theory.
The Chromosomal Imbalance Theory Of Cancer videos, to which David refers, can be found here.